Structural Elucidation of an Unknown Biologically Active Organic Compound Isolated from Myanmar Indigenous Medicinal Plant Curcuma Petiolata (MA-LA)

Author: Aye Aye Cho1, Myint Myint Sein2 , Mya Aye3

Abstract:

         A potent unknown compound was isolated from rhizomes of Myanmar indigenous medicinal plant, Curcuma Petiolata, by using modern separation technique, such as, Thin Layer Chromatogram (TLC) and Column Chromatography. Recrystallization of this compound gave rise to colorless needle shape crystals. The yield is found to be 1.38% based upon the crude extract. This compound responded the highest activities on six tested organisms namely Bacillus subtilis, Staphylococcus arureus, Pseudomonas aeruginosa, Bacillus pumalis, Candida albican and Mycobaterium species. The molecular formula, C15H21O5N, and the planar structure of this compound could be elucidated applying advanced spectroscopic methods, such as, FT-IR, 1H-NMR (600 MHz), 13C-NMR (150 MHz), DEPT, DQF-COSY, HSQS, NOESY and EI-Mass spectral data, respectively.

Published:  Myanmar Academy of Arts and Science Research Journal (Vol-IV, No-1, Jun 2006, Chemistry)